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Cervical Cancer: A Global Epidemic

Dr. Robert D. Hilgers, MD, MA, CAE, president and CEO of Women's Global Cancer Alliance, discusses cervical cancer.
Season 11 Episode 21 Length 27:29 Premiere: 02/28/16

About

Join host Dr. Wayne Tuckson, a colorectal surgeon, as he interviews experts from around the state to discuss health topics important to Kentuckians.


Funding for this program is made possible in part by:


About the Host

A native of Washington, D.C., Dr. Wayne Tuckson is a retired colon and rectal surgeon based in Louisville. For more than 20 years, he has served as host for Kentucky Health, a weekly program on KET that explores important health issues affecting people across the Commonwealth. A graduate of Howard University School of Medicine, Tuckson is a past president of the Greater Louisville Medical Society and is a recipient of the Community Service Award from the Kentucky Medical Society, the Thomas J. Wallace Award for “Leadership in Promoting Health Awareness and Wellbeing for the Citizens of Jefferson County” given by the City of Louisville and the Lyman T. Johnson Distinguished Leadership Award given by the Louisville Central Community Centers.


Cervical Cancer: A Global Epidemic

Over the past several decades, screening for cervical cancer in the U.S. has led to a dramatic reduction in mortality rates. In this country, getting a Pap test, a simple and effective screening test, is a common practice for women. The test identifies pre-cancerous cells and leads to effective treatment. However, cervical cancer mortality rates are far higher in developing countries, where resources and public education remain in scarce supply.

In this episode of Kentucky Health, host Dr. Wayne Tuckson talks with one of the world’s leading cervical cancer experts and activists about the challenges of implementing effective screening and treatment programs for the disease.

Dr. Robert D. Hilgers, MD, MAE, CAE, is professor emeritus at the University of Louisville School of Medicine. The gynecological oncologist has received numerous honors for his service, and he is the founder and CEO of the Women’s Global Cancer Alliance, which started in 2008. Prior to that, Dr. Hilgers founded the Kentucky Cervical Cancer Coalition in 2005.

It is now believed that most all cervical cancers are transmitted through sexual contact via the human papillomavirus (HPV). About 40 strains of HPV are transmitted via sexual contact.

According to Dr. Hilgers, “…80 percent of us have been infected with the human papillomavirus, at one time or another. Now, having said that, most of [the viruses] go away within 18 to 24 months. And, it’s only 5 percent or 10 percent that stick around, and are not permanent, but they simply persist.”

Genital warts are also spread through sexual contact via HPV but from two strains of HPV that are different from those that cause cervical cancer. Genital warts are easily detected and treated, but the strains of HPV that cause cervical cancer can lie dormant for 10 to 20 years.

“HPV infection is a silent infection,” Hilgers says. “… the period where the pre-cancer occurs, where you want to pick up with the screening – that’s a silent period as well. So here you’ve got a period of silence, and then all of a sudden the cancer shows up and you haven’t had any opportunity to prevent it.”

In the U.S. and other Western industrialized nations, the introduction of the Pap smear screening test during the 1940s greatly reduced cervical cancer incidence and death rates. Named after pathologist Dr. George Papanicolaou, who developed the screening method, the Pap test involves scraping tissue from the cervix (lower part of the uterus) and examining the cells for signs of the pre-cancerous condition known as cervical intraepithelial neoplasia.

If abnormal cells are detected, the cervix is closely inspected during a further diagnostic test called a colposcopy. If necessary, liquid nitrogen is used to destroy abnormal cells, a procedure that is 85 percent to 90 percent effective, according to Hilgers. Once cervical cancer is fully present, however, treatment is far more difficult.

Incidence Rates: A Result of Poverty
Pap tests are recommended for women beginning at age 21, with follow-ups every three to five years up to age 65. Public education about its effectiveness has been incredibly successful in reducing incidence rates for cervical cancer in the U.S. and Europe, as mentioned, but in certain regions rates remain relatively higher.

Hilgers notes that in Eastern Kentucky, incidence rates are higher than for the state overall. According to the Kentucky Cancer Registry, nine counties in Eastern Kentucky fall within the highest incidence range (over 12.6 per 100,000 persons) for years 2009-2013. The incidence rate for Kentucky for 2012 was 9.3 per 100,000 persons.

The reason for this higher rate? “Poverty and socioeconomic conditions,” according to Hilgers. “Really, I think that health is intrinsically linked to socioeconomic conditions, environments which people live in.”

Most importantly, people living in poverty lack access to regular screening, Hilgers adds. He notes that Eastern Kentucky has for decades lacked the medical resources, from doctors to supplies and hospitals, present in other areas of the commonwealth. The region has made improvements in its health care infrastructure in recent years, but still lags behind the rest of the state and the United States overall.

The Crisis in Haiti
For most of the past ten years, Hilgers’ focus has been directed overseas, to countries where cervical cancer incidence and mortality rates are national health emergencies. He says that more than 90 percent of all cancers of the cervix arise in women living in developing countries. For many of these countries, what little medical funding that exists is allocated to infectious, acute diseases such as HIV/AIDS, malaria, and tuberculosis – diseases that strike, progress, and spread rapidly, and are fatal if not immediately treated.

Hilgers’ mission with the Women’s Global Cancer Alliance is to bring international awareness of women’s cancers, and in particular cervical cancer, up to the level of these infectious diseases. Since serving on a medical team in Haiti following that country’s devastating earthquake in January 2010, Hilgers has started one cervical cancer prevention clinic in Haiti, with plans for another in the works. He is also working to establish a national cancer registry for Haiti.

According to the Haitian medical organization GHESKIO, Haiti has an incidence rate for cervical cancer of 94 per 100,000 population. In the United States, it is 7.7 per 100,000 as of 2012. In Haiti, Hilgers says that the cost of getting a Pap smear is prohibitive for all but the affluent.

This is due in part to the shortage of clinics, labs, and pathologists in the country. Hilgers says that Haiti has nine pathologists for a population of over 10 million people, and all of those are located in Port-au-Prince. If a Pap smear is administered in Haiti, results are often delayed for up to six weeks, Hilgers says, as opposed to 48 hours in the U.S.

Therefore, most screenings that are conducted in Haiti are colposcopies rather than Pap smears. Hilgers says that he is currently training his clinic’s director to perform colposcopies, and that the two nurses on staff already perform them.

Hilgers provides free screenings at his clinic, but Haitian women who are diagnosed with cervical cancer must travel to the Dominican Republic for radiation therapy. Radiation treatment is the best method available for cervical cancer patients, but the travel requirements add to the cost and make it too expensive for most.

“And, unfortunately, many of these women die of their disease, and their families are intact, and they still have kids in their formative years,” he says… It has a very disturbing, very fragmenting effect on the family.”

Hilgers says that his clinic has been open for about eight months, which is far too soon to begin to assemble data and measure its effectiveness. Given the scope of the problem in Haiti, and the lengthy amount of time it takes for HPV infection to develop into cervical cancer, it will be years before such evidence can be collected. But he is committed to speaking out about the global scale of this crisis, which he hopes will lead to more financial resources being applied to screening for cervical cancer in developing countries.

“The greatest issue that we face right now is that people are not aware of the problem,” he says. “People are not aware of the fact that you need to screen these women differently in developing countries, and that most of the cases now are in developing countries. … It’s a known fact that cancer of the cervix follows poverty – that’s true in the United States, and it’s true outside of the United States. You’re not going to get as much attention under those sort of circumstances, generally speaking. So we want to raise the level of awareness of this problem.”

Season 11 Episodes

Oral Health in Rural Kentucky

S11 E27 Length 27:35 Premiere Date 06/19/16

Addiction's Impact on the Family

S11 E26 Length 28:36 Premiere Date 06/05/16

Oral Health for Seniors

S11 E25 Length 27:14 Premiere Date 04/17/16

Complications of Pelvic Surgery

S11 E24 Length 27:45 Premiere Date 04/10/16

Common Eye Disorders

S11 E23 Length 28:17 Premiere Date 04/02/16

Hospice Care

S11 E22 Length 27:53 Premiere Date 03/27/16

Cervical Cancer: A Global Epidemic

S11 E21 Length 27:29 Premiere Date 02/28/16

PTSD: Not Limited to the Military

S11 E20 Length 27:09 Premiere Date 02/21/16

African American Health Care in Louisville

S11 E19 Length 27:26 Premiere Date 02/14/16

Human Trafficking

S11 E18 Length 28:20 Premiere Date 02/07/16

Preterm Infants and Their Care

S11 E17 Length 28:06 Premiere Date 01/31/16

Help for Teenage Parents

S11 E16 Length 27:32 Premiere Date 01/24/16

Health News We Need to Know

S11 E15 Length 28:06 Premiere Date 01/17/16

Diagnosing and Treating Dyslexia

S11 E14 Length 28:12 Premiere Date 01/10/16

The Diabetes Epidemic

S11 E13 Length 28:53 Premiere Date 01/03/16

Cancer in Kentucky: Are We Winning the War?

S11 E12 Length 27:27 Premiere Date 12/27/15

Adult Orthodonture

S11 E11 Length 27:24 Premiere Date 12/20/15

Stress and Adolescence

S11 E10 Length 27:11 Premiere Date 12/13/15

Crohn's Disease and Colitis

S11 E9 Length 27:04 Premiere Date 11/22/15

Advances in Telemedicine

S11 E8 Length 26:14 Premiere Date 11/15/15

Lung Cancer in Kentucky

S11 E7 Length 26:44 Premiere Date 11/08/15

Greater Louisville Medical Society

S11 E6 Length 26:49 Premiere Date 11/01/15

Cervical Disc Surgery

S11 E5 Length 27:03 Premiere Date 10/25/15

Training New Doctors

S11 E4 Length 28:37 Premiere Date 10/18/15

Best Practices for Prenatal Care

S11 E3 Length 27:19 Premiere Date 10/11/15

Knee Replacement

S11 E2 Length 26:28 Premiere Date 10/03/15

Chemotherapy: New Advances, a New Age

S11 E1 Length 26:22 Premiere Date 09/26/15

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